ITSN1 and Parkinson disease: A recent report also found an enrichment of rare (MAF < 0.1%) ITSN1 PTVs among PD cases (n = 5 out of 4,668) versus controls (n = 36 out of 355,276) in the deCODE Icelandic population7 (Fisher’s exact test [FET] p = 1.9 × 10−4; OR [95% CI] = 10.6 [3.2, 27.1]).