However, ITGB1 was found to be nonspecificallyexpressed in glioblastoma tissue according to spatial transcriptomicanalyses, despite the high ITGB1+ EV counts in glioblastomapatients, which is also supported by the literature,9,25,26 suggesting that much of thisfraction is contributed by the TME. The gene discussed is ITGB1; the disease is glioblastoma.