ITGAV and breast carcinoma: Integrin‐based cell surface receptors play a key role in promoting cancer cell invasion and migration through ECM remodeling, and overexpression of ITGAV has been reported in breast cancer as well.[57] We speculated that activation of the EDIL3–ITGAV axis could potentially evade immune cell function and promote migration of cancer cells through integrin‐based ECM remodeling.