Furthermore, a distinct subtype, namely complement 1q (C1Q+) Mφs with high expression of C1QA, C1QB, and C1QC, has recently been identified in various cancers playing crucial roles in modulating an immunosuppressive TME by regulating T‐cell function.[49] Consistent with these studies, we observed a higher expression of C1Q+ Mφ’s signatures, including C1QA, C1QB, and C1QC, within our Tri samples. This evidence concerns the gene C1QC and cancer.