Specifically, after treating the cells in Mono and Tri conditions with different dosages of Ro‐61‐8048 that targets the upstream enzyme of the KP/Trp pathway (Figure 8B), we monitored the invasion of cancer cells into the stromal region for 48 h post‐treatment and compared the migration distance relative to the control (no drug) group as well as between conditions. This evidence concerns the gene NPPA and cancer.