Previous studies have reported that CXCL9:SPP1 macrophage polarity is a good choice for selecting anti‐ or pro‐tumor macrophages in sarcoma,[18] we also examined changes in the CXCL9:SPP1 polarity of PBS‐BMDMs and OCDM‐BMDMs after 24 h of coculture with apoptotic OS cells. This evidence concerns the gene CXCL9 and neoplasm.