A Chinese DM cohort also found a significant difference in VCAM-1 levels between anti-MDA5 positive vs. negative patients but such difference by the presence or absence of the antibody was not seen in other antibody groups including antisynthetase ab, anti-TIF1 ab, anti-mi2 ab, and anti-NXP2 ab [26]. The gene discussed is IFIH1; the disease is diabetes mellitus.