Cells or microparticles detached from the endothelium, selectin proteins induced by cytokine stimulation that is more specific to endothelial cells, coagulation factors including von Willebrand Factor which transports factor VIII in response to activation of the endothelium, cytokines and interferon related chemokines are additional biomarkers of vasculopathy that have been studied [37]. This evidence concerns the gene VWF and vascular disorder.