APOA1 and interstitial lung disease: Associations between plasma lipoproteins with subclinical ILD in the Multi-Ethnic Study of Atherosclerosis cohort showed greater HDL-cholesterol and ApoA-1 (the major protein component of HDL) levels associated with less subclinical lung inflammation on CT and biomarkers of lung injury (SP-A and MMP-7) independent of demographics, smoking and inflammatory markers [30].