Of note, the IL-17 signaling pathway was also enriched in this KEGG pathway analysis, which is consistent with the result of the KEGG pathway enrichment analysis based on RNA-seq. As detected by RT-qPCR assay, the correlation between CARHSP1 and IL-6 was always significant across all the PCa cells and the two knockdown sequences (Fig. S4A). Here, CARHSP1 is linked to posterior cortical atrophy.