On the other hand, Kiełb P. et al. reported that IL-17 A and IL-17RA expressed in both prostate tissue and lymph node metastases, highlighting the potential significance of IL-17 A and IL-17RA in PCa metastasis and premetastatic niche formation [23]. This evidence concerns the gene IL17RA and metastatic malignant neoplasm in the lymph nodes.