Immunohistochemical analysis of K8484/GFP/CEA liver metastases with anti-αvβ6 antibodies confirmed the presence of this integrin in tumor tissues (Fig. 5B), whereas imaging studies with 5a-IRDye800, administered intravenously to tumor-bearing mice, showed efficient accumulation of this conjugate in metastatic colonies in vivo (Fig. 5C). The gene discussed is CEACAM5; the disease is neoplasm.