According to this view, it has been reported that anti-αvβ6 antibodies can inhibit the growth of αvβ6-positive tumors through a TGFβ-regulated mechanism [17], whereas other studies have shown that antibodies against αvβ8 can inhibit the activation of TGFβ in murine tumors and induce durable anti-tumor immunity [11, 18]. Here, TGFB1 is linked to neoplasm.