Recent research demonstrated that autophagy in pancreatic cancer (with ~98% RAS mutation) impedes immune recognition of cancer cells by degrading MHC-I.21 To explore the possible involvement of immune regulation in the observed superior effect of PI4KB-Peptide-1, we analyzed MHC-I levels in the tumors (Fig. 10d–f). The gene discussed is PI4KB; the disease is familial pancreatic carcinoma.