THRSP and hepatocellular carcinoma: Western blotting and IHC on tissue microarrays confirmed the decreased THRSP protein expression in HCC, with THRSP levels emerging as an independent prognostic factor for both overall survival (OS) and recurrence-free survival (RFS) in patients with HCC (Fig. 1F, G; Supplementary Fig. S1E; Supplementary Tables S3, 4).