Their antigen-specific phagocytosis of ovarian cancer cells was preliminarily verified in vitro and in vivo.1061 Preclinical studies of CAR-M have reported promising results in anti-PSCA against pancreatic cancer.1062 The phase 1, first-in-human (FIH) study of the anti-HER2 CAR-M, CT-0508 (NCT04660929), and CT-0525 (NCT06254807) in subjects with HER2 overexpressing solid tumors is ongoing. The gene discussed is ERBB2; the disease is pancreatic neoplasm.