CD47 is a glycoprotein highly expressed in many types of tumor cells, and the Inhibition of CD47 binding to SIRPɑ on macrophages could promote the repolarization of TAMs from M2 to M1.1090 Zhou et al. developed a BBB-penetrating nano-capsule named NAcp@CD47 to deliver anti-CD47 antibodies and STING agonists. Here, SIRPA is linked to neoplasm.