Recent studies have shown that 1-stearoyl-2-15-HpETE-sn-glycero-3-phosphatidylethanolamine (SAPE-OOH) is an important surface marker of ferroptotic tumor cells and binds to TLR-2 on the surface of macrophages, promoting the phagocytosis of ferroptotic tumor cells by macrophages. The gene discussed is TLR2; the disease is neoplasm.