,22,23 Furthermore, the presence of CXCL13+ T cells has been associated with enhanced anti-PD-1 responses in various cancers such as non-small cell lung cancer (NSCLC),22,24 high-grade serous ovarian cancer,25 and others,23,26,27 where their high infiltration correlates with improved prognoses in certain contexts.28 The gene discussed is CXCL13; the disease is cancer.