EML4 and cancer: To investigate whether the novel TTC7A-ALK fusion protein contributes to tumorigenesis, we constructed stable expression of TTC7A-ALK or EML4-ALK variant 1 (the most common EML4-ALK fusion subtype) in three non-cancer cell lines commonly used to assess carcinogenicity (HEK-293T cells, NIH3T3 fibroblasts and Ba/F3 cells).