The 2 SNPs discarded by the Midrange Filter are located within genes associated with phenotypes unrelated to the mental health diagnoses of the PsyCourse participants: KCNH1 is associated with epilepsy (Tian et al. 2023) and severe and rare development disorders (Gripp et al. 2021), while TMEM200A is associated with gastric cancer (Deng et al. 2023). This evidence concerns the gene TMEM200A and gastric cancer.