The overlap between DA and DE risk genes was minimal with only two genes (Fig. 4C, gray dots), hyperpolarization-activated cyclic nucleotide-channel 2 (HCN2) and IN080 complex subunit E (INO80E), being both DE (FCs = 0.36 and 0.26 and FDR = 0.06 and 0.09, respectively) and DA (FCs = 0.14 and 0.16 and FDR = 0.05 and 0.03, respectively) for schizophrenia risk in excitatory neurons’ layers 2/3 (Exc_L2-3). Here, INO80E is linked to schizophrenia.