The mean percentages of LAP+ cells in CD4+ T cells, CD8+ T cells, B cells, and granulocytes significantly increased on day 7 after tumor inoculation (29.7%, 32.9%, 35.1%, and 50.4%, respectively) and they decreased on day 34 (16.4%, 16.9%, 24.7%, and 10.9%, respectively) (Fig 3K, S7 Table). This evidence concerns the gene TGFB1 and neoplasm.