FTO and colorectal cancer: GAS5 was reported to be negatively regulated by the m6A reader YTHDF3 and involved in the progression of colorectal cancer.28 In addition to being a “writer” and “reader,” the “eraser” FTO was also reported to reduce the m6A modification of GAS5 and promote the EMT process and inflammatory response in the process of renal interstitial fibrosis.29 However, in the highly contractile state of labor onset, METTL3 and IGF2BP1 exhibit different GAS5 modifications compared with YTHDF3 and FTO.