The genes associated with HAE-nC1INH include F12, the gene for coagulation factor XII (FXII); PLG, the gene for plasminogen; ANGPT1, the gene for angiopoietin-1; KNG1, the gene for kininogen-1; MYOF, the gene for myoferlin; and HS3ST6, the gene for heparan sulfate glucosamine 3-O-sulfotransferase-6 (HS3OST6). Here, HS3ST6 is linked to hereditary angioedema.