Similar to the passive ITP mice, YC‐4‐3 significantly decreased the percentage of CD80+CD86+ M1 macrophages (Figure 5B), repressed the expression of CD64, and increased CD32B on macrophages in the spleen (Figure 5C) and bone marrow (Figure 5E). This evidence concerns the gene FCGR1A and autoimmune thrombocytopenic purpura.