Though some studies have also identified that there is an association between APOE4 with DLB (Tsuang et al., 2013; van der Lee et al., 2018; Shiner et al., 2021; Nasri et al., 2022; Bousiges et al., 2023), the role of APOE4 toward DLB pathogenesis and its associated cognitive impairment also still remains unclear. Here, APOE is linked to Cognitive impairment.