all PiB+ subjects were demented (DLB and PDD), had higher prevalence of APOE4, and lower MMSE scores when compared to PiB- subjectsPiB+ subjects had increased [11C]-PiB uptake in posterior cingulate, cuneus, precuneus, striatum temporoparietooccipital cortex, and frontal cortex. This evidence concerns the gene APOE and Lewy body dementia.