APOE and Parkinson disease: To correspond, Shang et al. (2020) examined in 28 Chinese individuals with PD-MCI and APOE4 that significantly lower functional connectivity values between the bilateral caudate nucleus and posterior cortical regions, including the right superior occipital and middle temporal gyrus, was significantly associated with reduced semantic fluency scores when compared to PD-MCI APOE2 and APOE3 carriers (Shang et al., 2020).