Similarly, Akhtar et al. (2017) also found that higher amyloid-beta (via [18F]-AV-45 PET SUVR) in memory-related brain areas, including the anterior and posterior cingulate, precuneus, as well as temporal, frontal and parietal cortices, was associated with APOE4 in their PD-MCI and PD-NC groups when controlling for age (Akhtar et al., 2017). The gene discussed is APOE; the disease is Parkinson disease.