Univariate analysis showed that (Table 5), KPS score < 80 (HR 2.30, 95%CI [1.09–4.84], p = 0.028), albumin <40.0 g/L (HR 1.68, 95%CI [1.02–2.79], p = 0.044), T stage (3-4) (HR 2.73, 95%CI [1.09–6.82], p = 0.032), N stage (2-3) (HR 1.88, 95%CI [1.14–3.11], p = 0.014), TNM stage (III-IV) (HR 1.68, 95%CI [0.95–2.97], p = 0.075), tumor location (middle and lower chest) (HR 1.73, 95%CI [0.97–3.10], p = 0.063) and sarcopenia (HR 2.05, 95%CI [1.12–3.74], p = 0.020) were the adverse factors of OS. The gene discussed is ALB; the disease is sarcopenia.