Flow cytometry can aid in the diagnostic approach for ALCL through the examination of tissue samples, effusions, and peripheral blood samples in patients with signs of local inflammation after implant-based breast augmentation as tumor cells usually express the phenotype CD3+/CD4+/CD30+/ALK- and CD3+/CD8+/CD30+/ALK- [40-42]. The gene discussed is CD8A; the disease is neoplasm.