AFG3L2 and infection: The rise in lysophosphatidylcholine, a lipid involved in inflammatory responses, points to a potential inflammatory state in patient cells, consistent with previously reported neuroinflammatory aspects of AFG3L2 (Knuplez and Marsche, 2020; Liu et al., 2020); however, MRI results showed no signs of neuroinflammation, although clinical follow-ups reveal a higher infection susceptibility.