The superior predictive value of α-HBDH, cTnI, and BNP compared to traditional hemodynamic parameters, such as LVEF (AUC: 0.883 vs. 0.712, P < 0.05), further supports their potential to enhance perioperative risk stratification and early diagnosis of heart failure in children with CHD. This evidence concerns the gene TNNI3 and coronary artery disorder.