For the diagnostic analysis, the ROC curves indicated that PCBP2 has high diagnostic potential across various cancers [Fig. S6(d)].To investigate the function of PCBP2 in PCa, we performed knockdown experiments using two strands of siRNA targeted at PCBP2 and validated their efficiencies by qRT-PCR [Figs. 7(h) and 7(i)]. This evidence concerns the gene PCBP2 and posterior cortical atrophy.