The heatmap illustrates the differential expression of these 13 OSRDEGs between keloid and normal skin tissues (Figure 2D), where F3, FOXL2, EDN1, and NTF3 show higher expression in keloid tissues, while BDNF, FLT1, VCAM1 and ADRB2 are more highly expressed in normal skin. This evidence concerns the gene VCAM1 and keloid.