The findings show no significant association between the TGF-β1 T869C gene polymorphism and susceptibility to autoimmune diseases (T vs. C: OR = 1.163, 95% CI = 1.010-1.339, P = 0.036; TT vs. CC: OR = 1.398, 95% CI = 1.074-1.820, P = 0.013; TT vs. TC + CC: OR = 1.156, 95% CI = 0.966-1.382, P = 0.113; TT + TC vs. CC: OR = 1.219, 95% CI = 0.998-1.504, P = 0.065; TC vs CC: OR = 1.151, 95% CI = 0.950-1.395, P = 0.151). The gene discussed is TGFB1; the disease is autoimmune disease.