Abnormalities in polycystin 1 and 2 (PC1 and 2), encoded by PKD1 and PKD2, the causative genes of ADPKD, activate various signaling pathways, including the mammalian target of rapamycin (mTOR) system, leading to abnormal cell proliferation [1,2]. This evidence concerns the gene PKD1 and autosomal dominant polycystic kidney disease.