SQSTM1 and Sepsis: The mean fold-change in intracellular p62 levels were significantly elevated when compared to the healthy controls in the C19wSepsis cohort (> 14-fold increase, ****p<0.0001) and Sepsis Alone cohort (> 3-fold increase, **p=0.0017), while the C19NoSepsis cohort showed no significant difference in the mean fold-change in the intracellular levels of p62 when compared to healthy controls (p>0.05) (Figure 7E; Table 3).