CASP3 and Sepsis: The mean fold-change in % gated cell population with respect to controls for the four cell death markers (caspase-1, caspase-3, MLKL and p62), two cytokines (IL-1-beta and IFN-gamma) and two MHCs (MHC I-A and MHC II-DRB1) observed for C19wSepsis, C19NoSepsis and Sepsis Alone clinical cohorts differed markedly in intracellular molecular signatures from those observed for the control cohort (Figure 7; Table 3).