The mean fold-change in intracellular LC3B levels in the C19wSepsis cohort were significantly higher compared to that in healthy controls (> 7-fold increase, ***p=0.0008); in contrast, the intracellular LC3B levels in the C19NoSepsis cohort showed a significant decrease (> 3-fold decrease, *p=0.0308), while the Sepsis Alone cohort showed an increase in intracellular LC3B but no significant difference when compared to that in healthy controls (p>0.05) (Figure 7D; Table 3). This evidence concerns the gene MAP1LC3B and Sepsis.