For example, mutation of TP53, which is the most common mutation pattern in breast cancer, was found in 80% of AcCC cases, but this mutation was not detected in salivary gland AcCC (18); however, AcCC aggressiveness is far less than triple-negative breast cancer (4); in terms of clinical manifestations and morbidity are also quite different (5). Here, TP53 is linked to acinar cell carcinoma.