The special point is that the progesterone receptor (PR) is weakly positive and shows positive for E-cadherin, though no genetic testing has been performed, and our case also showed 70% of ki- 67 high expression.Due to the rarity of AcCC and the limited number of reported cases, there is a lack of clear diagnostic criteria for AcCC, both in salivary gland cancers and breast cancers. The gene discussed is CDH1; the disease is acinar cell carcinoma.