Genomic abnormalities in some types of primary salivary gland tumors can also be detected in salivary gland-like primary tumors of the breast (e.g., polymorphous adenocarcinoma with HMGA2 or PLAG1 rearrangement; Secretory carcinoma with T (12; 15) fusion with ETV6-NTRK3; or adenoid cystic carcinoma with t(6; 9), resulting in MYB-NFIB fusion) (14).AcCC commonly occurs in salivary glands and resembles salivary gland acinic cell carcinoma morphologically when found in the breast. The gene discussed is PLAG1; the disease is salivary gland acinic cell carcinoma.