METTL14 and leukemia: Furthermore, several studies have shown that dysregulation of m6A regulatory factors plays a crucial role in leukemia, and alterations in the mRNAs they target (such as METTL14 and FTO) may be associated with the development of drug resistance [Yan et al., 2018; Weng et al., 2024; Hsu et al., 2017].