Recent studies have revealed PTL’s potential to induce apoptosis in various cancer cell lines, including acute lymphoblastic leukemia (Ortiz-Reyes et al., 2024), melanoma (Dorostgou et al., 2024), lung cancer (Cai et al., 2024), colorectal cancer (Liu Y. C. et al., 2017), and pancreatic cancer (Liu W. et al., 2017; Denda et al., 2024). The gene discussed is PNLIP; the disease is colorectal cancer.