NIBAN2 and osteoporosis: A significant decrease in osteoblast activity and a slight increase in osteoclastic activity were observed in our enrolled samples, which was consistent with the typical pathological phenotype of senile osteoporosis (Figure S7d,e, Supporting Information).[15] Bone tissues from the osteoporosis patients exhibited significantly lower expression levels of NIBAN2 and RUNX2 exon 6‐inclusive ratio than those from the control non‐osteoporosis patients (Figure7a,b).