Moreover, we observed that DNMT1 overexpression or miR-34a-5p inhibitor was able to antagonize the effect of FVTF on FoxM1 expression (Fig. S5D and E), supporting that FVTF inhibits HCC cell stemness via targeting DNMT1/miR-34a-5p/FoxM1 axis. Here, DNMT1 is linked to hepatocellular carcinoma.