We recently screened cancer stem-related genes and miRNAs regulated by FVTF in HCC cells, and identified and confirmed that DNMT1 and FoxM1 were obviously downregulated, whereas miR-34a-5p was obviously upregulated by FVTF, indicating that DNMT1, miR-34a-5p and FoxM1 could be the targets of FVTF in the HCC cells. This evidence concerns the gene DNMT1 and cancer.