Attraction of mobilized neutrophils to the tumor site is realized via chemokines CXCL1, CXCL2, CXCL5, CXCL6, and CXCL8 (IL-8) through CXCR1/2 and CXCL12 (SDF-1) and its receptor CXCR4 [77]. This evidence concerns the gene CXCR4 and neoplasm.