Paeoniflorin also decreases the levels of pulmonary fibrosis markers (type IV collagen, α-smooth muscle actin, hyaluronic acid, laminin, and procollagen III) and downregulates the expression levels of type I collagen (Col I) and type III collagen (Col III) in lung tissues, thus improving pulmonary fibrosis. The gene discussed is LAMB2; the disease is pulmonary fibrosis.