HDAC4 and Ataxia-telangiectasia: Similarly, the nuclear accumulation of Histone Deacetylase 4 (HDAC4), an epigenetic regulator implicated in several neurodegenerative disorders—including stroke, PD, AD, and ataxia telangiectasia—also disrupts dendrite architecture of mature neurons by negatively affecting VEGFD expression [252–257].