Given that serum levels of glyceraldehyde-derived AGEs, which could include MG-H1, are associated with insulin resistance and decreased adiponectin levels (Hyogo et al. 2007), circulating MG-H1 levels may also be a novel biomarker of adipose tissue inflammation, disturbed adipocytokine expressions, and insulin resistance in type 2 diabetes. The gene discussed is ADIPOQ; the disease is type 2 diabetes mellitus.