AGER and diabetic kidney disease: A growing body of evidence from in vitro-, animal, and clinical observational studies have suggested the pathological involvement of AGE-RAGE-ROS axis in the development and progression of diabetic kidney disease (Matsui et al. 2017; Yamagishi and Matsui 2013; Tsuchida et al. 1999; Wendt et al. 2003; Flyvbjerg et al. 2004; Kaida et al. 2013; Yamagishi and Imaizumi 2005; Reiniger et al. 2010; Grosjean et al. 2018; Yamamoto et al. 2010; Adeshara et al. 2022; Semba et al. 2010, 2009; Yubero-Serrano et al. 2015).