MICU3 and nervous system disorder: Evidence suggests that various diseases, including cardiovascular and neurological disorders, are closely associated with this process.376–378 Recent studies have revealed that MICU3 can form a disulfide bond with MICU1 at the Cys515 site, thereby enhancing calcium uptake by mitochondria.379 This suggests that the redox modification of MICU3 may finely regulate mitochondrial calcium influx, consequently modulating the progression of human diseases.