To ascertain whether treatment with A. muciniphila prevented cognitive impairment by inhibiting hippocampal NLRP3‐mediated neuroinflammation activation, we assessed the expression levels of ASC, Cleaved Caspase 1, IL‐18, NF‐κB, p‐NF‐κB and NLRP3 in the hippocampus after the behavioral study (Figure 6A,B). Here, CASP1 is linked to Cognitive impairment.