Intermittent hyperglycaemia increases oxidative stress‐related cell apoptosis in vascular endothelial cells through PKC‐dependent activation of NAD(P)H oxidase [29] and the expression of several adhesion molecules, such as ICAM‐1, VCAM‐1, and E‐selectin [30]. The gene discussed is ICAM1; the disease is Hyperglycemia.