IFNG and viral infectious disease: Because of the association of TEMRAs with viral infections, which are features of steroid-resistant SA in both children (38) and adults (37), and their propensity for IFN-γ secretion, TEMRAs are also a potential source of IFN-γ in SA in addition to effector/memory and tissue-resident memory (TRM) T cells (6, 10, 33, 35).