The CC-motif chemokine receptor type 5 (Ccr5), which interacts with CC-motif chemokine ligand 8 (Ccl8), was highly expressed in the lupus brain and suppressed by MSCT, as revealed by the RNA-seq data and confirmed by PCR (Figure 3, C and D). This evidence concerns the gene CCR5 and systemic lupus erythematosus.