TRIM38 and colorectal carcinoma: Furthermore, four types of CRC cell lines (DLD‐1, HCT116, RKO, SW480) were treated with different doses of 5‐Aza‐2′‐deoxycytidine (5‐Aza), and the results of qRT‐PCR and western blot showed that the mRNA expression and protein levels of TRIM38 were significantly positively correlated with the dose of 5‐Aza (Figure 1N,O).