However, in murine model of unilateral ureteral obstruction (UUO), ATG5 deficiency in proximal tubular epithelial cells aggravated kidney fibrosis by regulating G2/M cell cycle arrest and NF‐κB signaling.[7, 28] The discrepancy between our research and Mao et al.[28] may be attributable to the differences of the models used. This evidence concerns the gene ATG5 and Ureteral obstruction.