Univariate analysis highlighted several factors negatively affecting the BI: advanced age, hypertension, elevated serum glucose and CRP levels, decreased serum albumin and eGFR, lower initial GCS scores, higher NIHSS scores both initially and 24 h post-ER, immobility-related complications, extended hospitalizations, impaired ability to sit independently without physical assistance, compromised ability to sit independently for 2 min, thalamic haematoma locations, larger ICH volumes, the presence of intraventricular haemorrhage, and higher ICH scores. The gene discussed is CRP; the disease is Hypertension.