[37] identified that patients with altered ASXL1, either through chromosomal deletion or somatic mutations (ASXL1del/ ASXL1mut), had lower OS compared to patients with ASXL1wt in isolated del(20q) MDS (median OS: 25 vs. 65 months, p = 0.009). This evidence concerns the gene ASXL1 and myelodysplastic syndrome.