APOM and chronic kidney disease: Stratifying patients by eGFR in our initial analysis of the CARE FOR HOMe study revealed a decrease in plasma APOM levels in advanced CKD compared with early CKD stage G2, consistent with previous research showing that APOM decreases from CKD stage G3.11 The normal plasma concentration of APOM in healthy individuals is ≈0.9 μmol/L, similar to patients with only mildly reduced eGFR within CKD stage G2 in our cohort.25,26 Our analysis revealed a consistent decrease in plasma APOM with worsening CKD stage.