Between-group differences in NHHR quartiles were observed between the variables of age, sex, race, hypertension, DKD, physical activity, lipid-lowering drugs, PIR, BMI, HbA1c, FPG, ALT, AST, eGFR, UA, BUN, Ucr, TG, TC, HDL-C, and LDL-C (p < 0.05). The gene discussed is GPT; the disease is Hypertension.