We observed that CD71, TDGF1, and TOP1 are some of the most critical targets in cervical, ovarian, and uterine tumors, closely related to the survival/proliferation of cancer cells; ERBB2, EGFR, EGFR VIII are closely associated with the survival/proliferation of cervical cancer cells; other common basic targets include FLT3 in ovarian cancer. The gene discussed is TOP1; the disease is cervical cancer.