After PSM, no analyzed factors were significantly related to the incidence of anastomotic leak, including age, sex, body mass index (BMI), serum albumin level, previous abdominal surgery, diabetes mellitus, hypertension, hyperlipidemia, preoperative ileus, cancer stage, tumor location, operative approach, tumor size, and ostomy creation (Table 2). The gene discussed is ALB; the disease is Hypertension.